Sign In | Join Free | My
Nanjing Bangnuo Biotechnology Co., Ltd
Professional manufacture steroid powders , Injection steroid liquid , Peptides , HGH176-191, Sarms , Pharmaceutical raw materials ( Phenacetin ) , GBL , Local anesthetics , BB , BA etc.
Home > Selective Androgen Receptor Modulators >

White Powders Antidiabetic Active Pharmaceutical Ingredients Nateglinide 105816-04-4

Nanjing Bangnuo Biotechnology Co., Ltd
Trust Seal
Verified Supplier
Credit Check
Supplier Assessment

White Powders Antidiabetic Active Pharmaceutical Ingredients Nateglinide 105816-04-4

Brand Name : NJBN
Model Number : 105816-04-4
Certification : ISO9001 , SGS , KOSHER
Place of Origin : MADE IN CHINA
MOQ : 10g
Price : Checking
Payment Terms : T/T, Western Union, MoneyGram, Bitcoin
Supply Ability : 1000kg per month
Delivery Time : 5~8 working days
Packaging Details : 1kg/25kgs
Alias : Nateglinide
Purity : 99%
Appearance : White powders
Package : 1kg/25kg/piece
Dispatch time : Within 24h after payment
Stock : Available
Samples : Free
Contact Now

Pure Quality Antidiabetic Active Pharmaceutical Ingredients Nateglinide 105816-04-4

Product Name: Nateglinide
Synonyms: (-)-n-(trans-4-isopropylcyclohexanecarbonyl)-d-phenylalanine;ay4166;Nateglinide(H);trans-d-phenylalanin;trans-n-((4-(1-methylethyl)cyclohexyl)carbonyl)-d-phenylalanine;3-phenyl-2-(4-propan-2-ylcyclohexyl)carbonylamino-propanoic acid;A-4166;STARLIX
CAS: 105816-04-4
MF: C19H27NO3
MW: 317.42
Product Categories: Active Pharmaceutical Ingredients;API;APIs;Health & Beauty;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;STARLIX;Antidiabetic
Melting point : 137-141°C
Storage temp. : Room temp
Chemical Properties : White Cyrstalline Solid
Usage : antidiabetic KATP channel blocker
Usage : An Amino-acid derivative that stimulates insulin secretion. Used as an antidiabetic .

Nateglinide Hypoglycemic agents

Nateglinide and mitiglinide, repaglinide are three commonly used non-sulfonylurea oral hypoglycemic agents for insulin secretion,it is successfully developed for the first time by the Japanese company Ajomoto , its chemical structure belongs to carbamoylmethyl-benzoic acid (CMBA), it belongs to D- phenylalanine derivatives, it is a new generation of antidiabetic drugs having amino acid structure ,it is an amino acid derivative prompting insulin secretion, it is also currently the only non-sulfonylureas insulinotropic agent having amino acid structure. The mechanism is mainly through binding the pancreatic β cell sulfonylurea receptor, blocking islet cell ATP-sensitive potassium channels, leading to membrane depolarization, causing the calcium channe lopen to promote insulin secretion. This product is a new type of meal blood glucose regulator, which can effectively control the postprandial blood glucose levels, with rapid onset, short duration of action, low incidence of cardiovascular side effects and hypoglycemia and other characteristics .

Oral bioavailability is 72%, after 15min it can produce insulin secretion effect, Tmax is 0.5 ~ 0.9 h, 0.2 h insulin levels achieve peak , after 1.5 h it is similar to placebo. The plasma protein binding rate is 99%. After reaching plasmapeak , plasma concentrations decline rapidly.T1 / 2 of oral administration of 120 mg and intravenous injection 60 mg of is 1.5 to 1.7 hours, and the plasma clearance is 7.4 hours. It is metabolized in the liver by isoenzyme CYP2C9 and CYP3A4 way. The main metabolites are products after isomeric oxidation,it can be hydroxyl, diastereomers, isopropyl isomer or unsaturated aliphatic isomers.The main metabolites in plasma and urine are metabolites after the hydroxylation of isopropyl methine family (me-thine carbon) . About 2/3 nateglinide is excreted from the fecal , and the rest is excreted in the urine. Such excretion way is beneficial to elderly Ⅱ diabetes mellitus with renal dysfunction. nateglinide eliminate T1 / 2 is 1.4 h, because nateglinide T1 / 2 is short, there is no report yet about the drug accumulation in the body . Long-term use of nateglinide does not produce drug-induced hypoglycemia caused by drug accumulation .It is used for the treatment of diet therapy, exercise therapy and mild to moderate non-insulin dependent (Ⅱ type) diabetes which taking α- glucosidase inhibitor can not control. The results show that: nateglinide can be used more physiologically for meal glucose control, there is less opportunity for contact with insulin and hypoglycemia which allows patients to flexibly plan scheduling mealtimes, which means there is medication while eating, not eating no medication .

Nateglinide Uses

It is used for the treatment of diabetes .

More products you may like

Dianabol 5050mg/ml
Winstrol 100 (Stanozolol)100mg/ml
Deca 250250mg/ml
NPP 200200mg/ml
Boldenone undecylenate300mg/ml
Testosterone 100 ( Oil agent )100mg/ml
Testosterone Cypionate250mg/ml
Testosterone Enanthate250mg/ml
Sustanon 250250mg/ml
Trenbolone Base100mg/ml
Trenbolone Acetate100mg/ml
Trenbolone Enanthate100mg/ml
Trenbolone hexahydrobenzylcarbonate50mg/ml
Drostanolone Propionate100mg/ml
Drostanolone Enanthate200mg/ml
Methenolone Enanthate100mg/ml
Methenolone acetate50mg/ml
TMT Blend 375375mg/ml
TM Blend 500500mg/ml
Triple Trenbolone 180180mg/ml
Supertest 450450mg/ml
Anomass 400400mg/ml
Tri Deca 300300mg/ml
Nandro Test 225225mg/ml
Equi Test 450450mg/ml

  • For more detailed information , pls feel free to contact me by the following ways :

Skype : njbnsteroid
WhatsApp : +8617327093119
E-mail :
Website :

Product Tags:

SARM steroids


anabolic SARMS

China Customized Inflatable Bumper Ball Game Bubble Adult Grass CE supplier

White Powders Antidiabetic Active Pharmaceutical Ingredients Nateglinide 105816-04-4 Images

Inquiry Cart 0
Send your message to this supplier
Enter your email please.
To: Nanjing Bangnuo Biotechnology Co., Ltd
Characters Remaining: (0/3000)
Inquiry Cart 0