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Nanjing Bangnuo Biotechnology Co., Ltd
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Raw Steroid Powders 13647-35-3 Trilostane For Breast Cancer Canine Cushing ′ s Disease Treatment

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Raw Steroid Powders 13647-35-3 Trilostane For Breast Cancer Canine Cushing ′ s Disease Treatment

Brand Name : NJBN
Model Number : 13647-35-3
Certification : ISO9001 , SGS , KOSHER
Place of Origin : MADE IN CHINA
MOQ : 10g
Price : Checking
Payment Terms : T/T, Western Union, MoneyGram, Bitcoin
Supply Ability : 1000kg per month
Delivery Time : 5~8 working days
Packaging Details : 1kg/25kgs
Alias : Trilostane
Purity : 99%
Appearance : White powders
Package : 1kg/25kg/piece
Dispatch time : Within 24h after payment
Stock : Available
Samples : Free
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13647-35-3 Trilostane For Breast Cancer Canine Cushing ′ s Disease Treatment



Product Name: Trilostane
Synonyms: TRILOSTANE;(2-alpha,4-alpha,5-alpha,17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car;17-beta)-ph;4-alpha,5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;4-alpha,5-epoxy-3,17-dihydroxy-5-alpha-androst-2-ene-2-carbonitrile;4-alpha-5-epoxy-17-beta-hydroxy-3-oxo-5-alpha-androstane-2-alpha-carbonitril;androstane-2-carbonitrile,4,5-epoxy-17-hydroxy-3-oxo-,(2-alpha,4-alpha,5-al;modrenal
CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Inhibitor;FULVICIN
Melting point 264 °C
Storage temp. -20°C Freezer
Chemical Properties : White powders
Usage : An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer
Usage : Antifungal, inhibits mitosis in metaphase .



Treatment of Cushing's syndrome


Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress. They are also necessary for the regulation of salt and water balance in the body. Trilostane helps prevent the production of corticosteroids, controlling the symptoms associated with these disorders.


Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.



Uses in dogs


Trilostane was withdrawn from the United States market in April 1994. However, it was approved in 2008 for the treatment of Cushing's disease (hyperandrenocorticism) in dogs.
It is also the first drug approved to treat both pituitary- and adrenal-dependent Cushing's in dogs.
1. has kidney or liver disease.
2. takes certain medications used to treat heart disease.
3. pregnant.
4. taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
5. had an allergic reaction to this or any other medicine.


The treatment of advanced breast cancer


Breast cancer is the most common type of tumor in women. Currently, for postmenopausal patients with hormone receptor-positive or unknown, clinical treatments unanimously recommend to be the preferred antiestrogen therapy, and the role of this therapy in delaying disease progression and improving survival time also has been affirmed and confirmed in numerous studies of breast cancer .


Trilostane (trade name Modrenal) developed by the biotechnology company has already been on the market. It can be used for the treatment of postmenopausal women that hormone-selective cancer has spread outside the breast. The pharmaceutical uses two ways to slow down the disease progression. For hormone-sensitive breast cancer, estrogen promotes the growth of cancer cells by acting to the two receptors. Estrogen receptor α is cancer accelerator, and estrogen receptor β is the brake. Modrenal strengthens estrogen adsorption to the estrogen receptor β, and weakens the adsorption to estrogen receptor α. Meanwhile it also acts on another loci AP1in cell DNA to reduce cell proliferation .



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FAQ

Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.

Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.

Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.

Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service

Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!

Q6: How should I pay?
A: We accept all kinds of payment ways. such as T/T, Western union, Moneygram , Bitcoin .

Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.

  • For more detailed information , pls feel free to contact me by the following ways :


Skype : njbnsteroid
WhatsApp : +8617327093119
E-mail : gearmanager@chembj.com
Website : www.realanabolicsteroids.com


Product Tags:

anabolic steroid hormones

      

raw hormone powders

      
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Raw Steroid Powders 13647-35-3 Trilostane For Breast Cancer Canine Cushing ′ s Disease Treatment Images

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